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This is the article by Alan E. Tracers are now routinely used to measure flow rates, study mixing patterns, and locate leaks in heat exchangers and pipelines. There are three principal ways to minimize injury to healthy cells from radiation therapy: 1 rotating the external beam around the patient, 2 creating radioisotopes only at the site of the malignancy, and 3 developing a method to deliver appropriate radioisotopes directly to the cancerous tissue.

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Boron is introduced into the patient as part of a special chemical carrier, so that it preferentially concentrates at the tumor site. Thus, they are ideal instruments to help farmers make the best use of limited water supplies and are now found on many large U. A neutron beam is then focused on the boron, producing alpha particles that destroy the malignant cells only in the immediate vicinity of the concentrated boron. Changes in molecular structure, including the inducement of desired chemical reactions, can be created in certain materials by appropriate exposure to radiation. Because alpha particles are typically stopped within one human cell from their point of origin, the intense radiation damage is quite localized. Thus the shelf life of many foods can be extended appreciably, and the presence of food-borne disease organisms such as Escherichia coli can be dramatically reduced. Although modern factories are the source of most of the products that we use daily, harnessed radiation in industry likely constitutes the most hidden use of this technology to ordinary citizens. Two of the most common technologies are single photon emission computed tomography SPECT and positron emission tomography PET , which are used to detect cancer. Until recently, the use of radiation to actually cure diseases was rather limited. This allows online measurements to be made nondestructively while the material being measured is in motion. Widespread acceptance of food irradiation by the general public has been slow, but there are several signs—particularly in the United States—that consumer acceptance is not far away. It is important to note that food processed by radiation does not become radioactive. The U. Another effective way to improve crop production is the development of new species—varieties that can better withstand heat or storm damage, have earlier maturing times to escape frost damage and allow crop rotation, resist diseases and droughts, provide better growth and yield patterns, deliver improved nutritional value, allow improved processing quality, and so on. Food irradiation is included in this mandate. Accelerators are used to deliver either protons to the target or beta particles, which are normally directed onto a target that secondarily produces x-rays. This is safer and cheaper than most other methods such as steam because it can be done after the item is packaged. Radioisotopes have also been used to develop vaccines that are effective against certain animal diseases. Materials development. Food irradiation involves subjecting food to carefully controlled amounts of ionizing radiation, such as beta particles or gamma rays, to break the DNA bonds of targeted pathogens. The imaging properties of radioisotopes allow modern nuclear medical specialists to measure the activity of some specific physiological or biochemical function in the body as a function of time. Bone and joint disorders, along with spinal disorders, also benefit directly from this routine use of radioisotopes. Half a century later, nuclear technology has had astounding economic and job impacts in the United States see Table 1. Food and Drug Administration FDA for medical use in the United States, radiation was a crucial component of their success in making it through the approval process. In order to have just localized damage, either beta or alpha emitters are needed. Neutron moisture gauges can measure the hydrogen component of water in both the plant and the surrounding soil. An example of the second approach is boron-neutron capture therapy. New drug testing. Measurements that are typically made in production lines include liquid levels, the density of materials in vessels and pipelines, the thickness of sheets and coatings, and the amounts and properties of materials on conveyor belts. Process control and plant diagnostics. Since I has a half-life of eight days, it effectively disappears within a few weeks. These gauges are also frequently used in the food industry such as in filling cereal boxes and the oil industry, where determining the density of liquids, solids, or slurries is important. Perhaps the largest success to date in using this technique occurred in Mexico. At the doses used, it is impossible for beta, gamma, or x-rays to make food radioactive. Eisenhower challenged scientists and engineers to harness the atom for humanitarian purposes in medicine, agriculture, and other non-power aspects of direct benefit. And the Farm Bill approved by Congress mandated that commodities such as meat and poultry that are treated by any technology approved by the U. Substantial testing must be done before new drugs are approved. Perhaps the most significant success story over the past half-century in harnessing radiation to serve modern humanity is found in the field of medicine. Nuclear diagnostic techniques are now routinely used throughout the industrial world to determine anomalies in the heart, brain, kidneys, lungs, liver, breasts, and thyroid glands. It is highly unlikely that automation in such industries would be possible without the use of radioisotopes. In addition, the food that does reach them can become unsafe to eat because of contaminants such as insects, molds, and bacteria. Therapeutic approaches. Many radioactive tracer techniques have been used to investigate the reasons for reduced efficiency in modern plant operations. Greater crop production. Today, well over half of all sterilized medical equipment used in modern U. The earliest use of radiation in the medical field occurred in World War I, when portable x-rays helped field surgeons save many lives. By attaching radioactive tracers to known quantities and varieties of fertilizers, it is possible to directly determine nutrient efficiencies as the labeled products are absorbed at critical locations in the plant. Radiation in high enough doses can kill microorganisms, so gamma radiation is used to sterilize dressings, surgical gloves, bandages, and other equipment routinely used during medical procedures. There remains a huge need to find new ways to increase food production and deliver food without spoilage to the growing global population. Its sterile shelf life is practically infinite as long as the package is not opened. For at least 80 percent of the new drugs approved by the U. Sterilizing medical equipment. One of the first therapeutic applications involved using iodine I to cure thyroid cancer. Radioisotopes, because of their unique imaging characteristics via particle emission , are ideally suited to deal with such questions—including material uptake, metabolism, distribution, and elimination of unwanted residues from the body. Although this can have substantial benefits, it is impossible to keep the radiation from killing or impairing healthy tissue in the immediate vicinity, especially if the beam must pass through healthy tissue to reach the malignancy. This can help to substantially reduce the amount of fertilizer required to produce robust yields. XX, No. The totals in terms of dollars and jobs are impressive, but perhaps the biggest revelation is that the atom has a substantially larger impact outside the nuclear power sector than in it. Major supermarkets have signed on to offer irradiated meat at some stores. Waltar alan. The equivalent figure elsewhere ranges from Indeed, the application of radiation techniques to the development of new crop varieties has probably provided the greatest global economic value of any form of harnessing radiation. Today, dental x-rays, chest x-rays, mammograms, and numerous other tests are used routinely in the medical and dental professions. Tragically, infestation and spoilage prevent one-fourth to one-half of the food produced in the world from reaching people. Most of the current therapeutic procedures deliver radiation to the patient externally. Improving Animal Health. One key area concerns the optimal use of natural pastures or commercially prepared feeds. Specialized radiation techniques—either directly bombarding seeds to alter DNA structures or irradiating crops to induce variations in the resulting seeds—can greatly accelerate the selection process. One of the prime advantages of food irradiation is that it sterilizes food without altering its form or taste. Farm animals have likewise benefited from the application of radiation techniques. The I then preferentially lodges in the thyroid gland, and the beta-emitting properties of this radioisotope subsequently target and destroy the thyroid malignancy. Since the thyroid has a special affinity for iodine, it is a relatively simple and straightforward matter to have a patient drink a carefully determined amount of I in a chemically palatable form of solution. Paper mills use them to measure the density of wet pulp accurately in the first stages of paper production. Radiation was the key element in the development of 89 percent of about 2, new crop varieties in the past 70 years; three-quarters of these irradiation-induced varieties were food crops, and the rest were ornamental flowers. Eradication of pests. As of , nearly 27 percent of the crops grown in China were developed this way. But x-rays, useful as they are, provide only a snapshot of a particular piece of the anatomy. Another cell-directed method involves attaching the radioisotope to a chemical that has a special affinity for the malignancy. This includes detecting how a product attacks a targeted disease and any possible side effects. Water is becoming quite scarce in many areas of the world. Food processing. Modern steel mills use such gauges to measure the thickness of rolled metals accurately at every moment during production. It can also interfere with physiological processes such as sprouting in potatoes or onions. To date, China has benefited the most from using radiation to improve crop species. Although many of these therapeutic applications of radiation are still in relatively early trial stages, the potential for success is enormous. Diagnostic techniques.